Hormone Replacement Therapy (HRT) Singapore (2026)

Hormone Replacement Therapy (HRT) in Singapore

Medically Reviewed By: Dr Jana Lim – MBChB, MMed (FM)
Last updated: May 26, 2026

What Is Hormone Replacement Therapy?

Hormone replacement therapy tools and medications for menopause and low testosterone.

Hormone replacement therapy (HRT) is a medical treatment that replaces or supplements hormones the body no longer produces in adequate amounts, typically due to menopause in women or age-related testosterone decline in men. The aim is to restore hormone levels closer to a physiological range so that symptoms associated with hormonal change become more manageable.

In women, HRT, or now known as menopausal hormone therapy (MHT), replaces oestrogen and is often combined with a progestogen such as progesterone. In men, HRT generally means testosterone replacement therapy (TRT), which restores testosterone in those with clinically low levels.

In Singapore, HRT is prescribed following a medical consultation and, where appropriate, hormone testing to confirm that treatment is suitable.

How Hormone Replacement Therapy Works

HRT works by introducing hormones that act on the same receptors as the body's natural hormones, supporting the regulation of processes affected by hormonal decline such as temperature control, mood, libido, energy, bone turnover, and sexual function.

The hormones used are delivered in different forms depending on your needs and tolerance:

  1. Oral tablets travel through the digestive system and liver before entering circulation.
  2. Transdermal patches and gels release hormones steadily through the skin.
  3. Injections release hormones gradually over several weeks.
  4. Local preparations such as vaginal tablets or creams act mainly at the site of application rather than throughout the body.

Because hormones interact with multiple body systems, doses are individualised and reviewed regularly by a doctor, with the aim of using the lowest level that adequately manages symptoms.

Who May Benefit from Hormone Replacement Therapy

Woman experiencing menopause hot flush symptoms at night in bed.
Man with low testosterone symptoms resting after light exercise.

HRT may be suitable for adults whose symptoms of hormonal decline affect daily life, where a doctor has assessed that treatment is appropriate. The severity of symptoms, medical history, and risk factors all influence whether treatment may be recommended.

HRT may be considered for:

  • Women with menopause symptoms that affect daily life, such as hot flushes, night sweats, mood changes, sleep disturbances, vaginal dryness, or painful intercourse.
  • Women with premature or surgical menopause, where ovarian function ends before age 40 or following surgical removal of the ovaries.
  • Men with persistently low testosterone levels confirmed on blood testing, particularly when symptoms such as fatigue, reduced libido, erectile dysfunction, or loss of muscle mass are present.

"Hormone changes affect more than physical health, often influencing mood, sleep, and energy. Hormone replacement therapy, when suitable, offers a structured way to address these changes and ease their impact on daily life."
Dr Jana Lim

"Hormone changes affect more than physical health, often influencing mood, sleep, and energy. Hormone replacement therapy, when suitable, offers a structured way to address these changes and ease their impact on daily life."

Dr Jana Lim

Types of Hormone Replacement Therapy

The main types of HRT are grouped by the hormones they replace and the individuals they are prescribed for.

Menopausal Hormone Therapy (MHT)

MHT replaces oestrogen, often combined with progestogen for women who still have a uterus. The combined regimen helps reduce the risk of endometrial thickening associated with oestrogen alone. Oestrogen-only therapy is generally reserved for women who have had a hysterectomy, since the protective role of progestogen is no longer required.

Local vaginal oestrogen therapy, such as vaginal tablets or creams, may be used for symptoms such as vaginal dryness or discomfort during intercourse.

Testosterone Replacement Therapy (TRT)

TRT restores testosterone in men with confirmed low levels on a blood test. It is typically delivered by long-acting injection or daily topical gel, depending on patient preference and treatment response. Treatment is paired with regular monitoring of testosterone levels, red blood cell count (haematocrit), and prostate health.

Bioidentical Hormone Therapy

Bioidentical hormones are chemically identical to those produced by the body. They may be prescribed within either MHT or TRT regimens as part of an individualised treatment plan, and remain subject to the same medical assessment, monitoring, and prescribing standards as conventional HRT.

Considering hormone replacement therapy or experiencing symptoms of hormonal decline? Speak with one of our male or female doctors to find out whether HRT is suitable for you. Book an appointment today.

Book Your Appointment Today

Potential Side Effects of Hormone Replacement Therapy

HRT can cause side effects, though many people tolerate treatment well and effects often settle within the first few months. The likelihood and type of side effects vary by hormone, dose, and route of delivery.

Side effects more commonly reported include:

  • Breast tenderness or fullness, more common with oestrogen
  • Nausea, headaches, or bloating, especially when starting oral preparations
  • Mood changes during the early weeks of treatment
  • Skin irritation at the application site for patches or gels
  • Acne or oily skin with testosterone therapy
  • Fluid retention at higher doses

Less common but more serious risks include venous thromboembolism, stroke, and certain hormone-sensitive cancers in MHT, and raised red blood cell count or worsening sleep apnoea in TRT. The likelihood depends on age, hormone type, dose, route, and personal medical history. Regular reviews allow side effects to be monitored and the regimen adjusted if needed.

When Hormone Replacement Therapy May Not Be Suitable

HRT is generally not recommended for individuals with conditions that may be worsened by hormone supplementation. It is typically avoided in:

Even when HRT is suitable, treatment generally starts with the lowest dose that adequately manages symptoms and is reviewed regularly to balance benefits against risks.

Hormone Replacement Therapy: What to Expect

Female hormone test results used for hormone replacement therapy assessment.

HRT typically involves:

Initial Consultation

Your doctor reviews your symptoms, medical history, family history, and current medications to assess whether HRT is appropriate.

Hormone Testing

A blood test measures relevant hormone levels. For men, this typically includes total testosterone, sometimes alongside related markers. For women, hormone testing is not usually required.

Treatment Plan and Prescription

Based on the results, and if HRT is suitable, your doctor recommends a hormone, dose, and delivery method, and explains potential side effects and what to expect.

Follow-Up and Monitoring

Reviews are usually scheduled within the first few months and then periodically, with dose adjustments and repeat testing as needed.

Disclaimer: This information is provided as a general guide and does not replace medical advice. The treatment process may vary based on your individual circumstances. Speak with a doctor for personalised guidance.

Cost of Hormone Replacement Therapy in Singapore

At ATA Medical, we offer HRT for men and women, where assessed as suitable by our doctors. Our prices are as follows:

Test/Treatment Price*^
Consultation From $65.40
Menopausal Hormone Therapy
Systemic MHT (Tibolone, Oral) $75.21
Systemic MHT (Progesterone, Oral) $43.60
Systemic MHT (Transdermal Oestrogen Gel) $35.97
Local Vaginal Oestrogen Therapy (Vaginal Tablet) $70.85
Testosterone Replacement Therapy
Testosterone Injection $381.50 / injection
Testosterone Gel $196.20 / box
Hormone Testing
Estradiol / Oestrogen (E2) $32.70
Follicle Stimulating Hormone (FSH) $32.70
Thyroid Function Test (TSH) $32.70
Vitamin D Deficiency Test $130.80
DEXA Bone Densitometry $141.70
Female Acne / Weight Gain Screen**
Testosterone, Estradiol, Progesterone, TSH, Cortisol, FSH, LH, Prolactin, DHEAS, SHBG
(May be recommended for those suspected of having hormonal acne)
$218
Comprehensive Deficiency / Hair Loss Screen
Folate, Vitamin B12, Vitamin D, Iron, Total Iron Binding Capacity, % Iron Saturation, Ferritin, Zinc, Magnesium, Free T4, TSH
$263.78
Women's Wellness (Full Body Screening) From $152
*Prices are NETT and inclusive of GST.
^Prices last updated on May 26, 2026. While every effort is made to keep pricing information up to date, please contact our team to confirm the latest rates.

**Recommended to be done during days 2–5 of menstrual cycle and between 8:30 AM and 10:00 AM for accuracy.

For your comfort, consultations are available with our male or female doctors. Please let us know your preference when booking your appointment.

Book a Consultation for Hormone Replacement Therapy

ATA Medical @ Tanjong Pagar

72 Anson Rd, #01-02 Anson House, Singapore 079911
Tanjong Pagar Station (EW15)
Mon–Fri: 8:30 AM – 12:30 PM, 1:30 PM – 5:30 PM
Sat: 8:30 AM – 12:30 PM
Sun & PH: Closed
Last appt: 5:15 PM (Mon–Fri), 12:15 PM (Sat)

ATA Medical @ Orchard

1 Orchard Blvd, #05-09 Camden Medical Centre, Singapore 248649
Orchard Boulevard Station (TE13)
Mon–Fri: 8:30 AM – 12:30 PM, 1:30 PM – 5:30 PM
Sat: 8:30 AM – 12:30 PM
Sun & PH: Closed
Last appt: 5:15 PM (Mon–Fri), 12:15 PM (Sat)

ATA Medical @ Jurong

21 Jurong Gateway Rd, #02-08 CPF Jurong Building, Singapore 608546
Jurong East Station (NS1/EW24)
Mon–Fri: 8:30 AM – 12:30 PM, 1:30 PM – 5:30 PM
Sat: 8:30 AM – 12:30 PM
Sun & PH: Closed
Last appt: 5:15 PM (Mon–Fri), 12:15 PM (Sat)

ATA Medical @ Novena

101 Irrawaddy Road, #09-01 Royal Square Medical Centre, Singapore 329565
Novena Station (NS20)
Mon–Fri: 8:30 AM – 12:30 PM, 1:30 PM – 5:30 PM
Sat, Sun & PH: Closed
Last appt: 5:15 PM (Mon–Fri)

Navigate to Us

ATA Medical (Anson House)

Nearest MRT: EW15 Tanjong Pagar

ATA Medical (Camden Medical Centre)

Nearest MRT: TE13 Orchard Boulevard

ATA Medical (CPF Jurong Building)

Nearest MRT: NS1/EW24 Jurong East

ATA Medical (Royal Square Medical Centre)

Nearest MRT: NS20 Novena

Frequently Asked Questions (FAQ)

The cost of hormone replacement therapy (HRT) in Singapore varies by hormone type, formulation, and dose. At ATA Medical, where both male and female doctors are available, consultations start from $65.40, with menopausal hormone therapy options from $35.97 to $75.21, and testosterone replacement therapy at $196.20 per box of gel or $381.50 per injection. Prices exclude hormone testing and follow-up reviews. Total cost depends on the regimen and monitoring schedule recommended after assessment.
Yes, many general practitioners can prescribe hormone replacement therapy (HRT), provided the clinic offers menopause or men's health services. Some GPs handle hormone testing and prescribing directly, while others refer to a gynaecologist, endocrinologist, or urologist for more complex cases. At ATA Medical, our doctors provide hormone testing and personalised HRT plans where assessed as suitable.
For some, hormone replacement therapy (HRT) can be a worthwhile option when symptoms of hormonal decline meaningfully affect daily life. Whether it is right for you depends on symptom severity, age, medical history, and personal risk factors. Some find significant symptom relief, while others prefer non-hormonal alternatives. A doctor can assess whether HRT is appropriate for you.
At 44, you are more likely in the perimenopausal stage rather than menopause itself. The average age of natural menopause is around 49 to 51, but it is normal for the transition to begin in the mid-40s. If symptoms such as irregular periods, hot flushes, or mood changes are affecting your daily life, it is best to consult a women's health doctor for assessment.
Hormone replacement therapy (HRT) may be considered if you have persistent menopause symptoms such as hot flushes, night sweats, vaginal dryness, sleep disturbances, or mood changes that disrupt daily life. In men, signs include fatigue, reduced libido, and loss of muscle mass linked to low testosterone. Because these symptoms can have other causes, it is advisable to consult your doctor for evaluation.
Hormone replacement therapy (HRT) is generally considered most suitable when started before age 60 or within 10 years of menopause, though suitability depends on individual cardiovascular, clotting, and cancer risk factors rather than a strict age cut-off. Beyond this window, the balance of potential benefits and risks tends to shift, particularly for cardiovascular and clotting risks. Whether HRT is suitable depends more on your medical history, symptoms, and goals than on age alone, so it is best to discuss your suitability with your doctor.
Common signs of low oestrogen include hot flushes, night sweats, vaginal dryness, painful intercourse, mood changes, sleep disturbances, reduced libido, fatigue, irregular periods, and difficulty concentrating. Some people also notice headaches, joint discomfort, or thinning skin. Because these symptoms overlap with thyroid issues and stress, it is advisable to consult a women's health doctor for evaluation if symptoms persist.
The most commonly reported signs of hormonal imbalance are irregular menstrual cycles, unexplained fatigue, mood changes such as irritability or low mood, sleep disturbances, and changes in weight or skin (including acne or hair thinning). Hormonal shifts can occur during menopause, perimenopause, thyroid disease, or stress. If symptoms persist or affect daily life, it is best to consult your doctor for evaluation.
Hormone replacement therapy (HRT) duration varies between individuals. Some women take HRT for a few years to manage symptoms, while others continue for longer under regular medical supervision. Doctors generally use the lowest effective dose and review treatment periodically to weigh benefits against risks. There is no fixed maximum; the right duration depends on symptom severity, age, and personal risk profile.
Hormone replacement therapy (HRT) is generally not advised for people with certain medical conditions, including a history of breast cancer, prostate cancer, or other hormone-sensitive cancers, active or past blood clots (such as deep vein thrombosis or pulmonary embolism), stroke or coronary heart disease, undiagnosed vaginal bleeding, untreated severe sleep apnoea (for testosterone therapy), or active liver disease. A medical assessment by a doctor is required to assess whether HRT is appropriate.
Perimenopause typically presents with irregular periods, hot flushes, night sweats, sleep disturbances, mood changes, vaginal dryness, and reduced libido. Some people also notice heavier or lighter bleeding, breast tenderness, or difficulty concentrating. These symptoms result from fluctuating hormone levels in the years leading up to menopause. If they affect daily life, it is advisable to consult a women's health doctor for assessment.
Frequently reported signs of hormonal imbalance include fatigue, mood changes, irregular periods, sleep disturbances, weight changes, hot flushes, reduced libido, acne or skin changes, hair thinning, difficulty concentrating, and digestive issues. The exact pattern depends on which hormones are affected, including oestrogen, progesterone, testosterone, thyroid, or cortisol. If these symptoms persist, it is best to consult your doctor, who can arrange relevant blood tests.