Metabolic Health Programme | AMILI Optimise Plus

MOH-Registered

Near MRT Stations

Same-Day Appointments

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A Data-Driven Approach to Weight, Blood Sugar, and Cholesterol

• 8-week programme combining gut microbiome testing, CGM, and targeted probiotics
• Personalised nutrition plan based on your biological data, not generic guidelines
• One-to-one coaching with structured video consultations and daily chat support
• All-inclusive pilot pricing at $400 before standard rates apply in Q3 2026

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Located in Tanjong Pagar, Orchard, Jurong & Novena

Medically Reviewed By: Dr Leonard Leng – MBBS, MMed (FM), GDOM, DWD
Last updated: Apr 14, 2026

AMILI Optimise Plus is an 8-week metabolic health programme that combines gut microbiome testing, continuous glucose monitoring, targeted probiotics, and one-to-one coaching to support sustainable metabolic change.

At ATA Medical, we deliver this programme in Singapore in partnership with AMILI, a precision gut microbiome company focused on Asian populations. Rather than prescribing a generic diet, the programme uses your personal biological data to build a plan around how your body actually responds to food, activity, and sleep.

You receive a gut microbiome report, real-time glucose readings from a wearable sensor, and structured guidance from a certified coach. Together, these inputs show you which foods and habits support your metabolism and which are working against it.

Your gut microbiome plays a direct role in regulating appetite, blood sugar, fat storage, and cholesterol. The 38 trillion microbes living in your digestive tract act as a metabolic command centre, producing hormones and metabolites (chemical byproducts of microbial activity) that shape how your body handles food.

• Appetite regulation – Gut bacteria produce GLP-1 and PYY, hormones that signal hunger and fullness to the brain. A disrupted microbiome can blunt these signals and drive persistent cravings.
• Blood glucose control – The balance of bacteria in your gut can influence how much sugar your liver releases into the bloodstream and how well your body responds to insulin, helping stabilise post-meal blood sugar.
• Fat storage patterns – Microbial imbalance is associated with low-grade inflammation in fat cells and a shift toward visceral fat accumulation around the abdomen.
• Lipid profile – Gut microbes influence how your body processes dietary fats and regulates cholesterol.

When these systems drift out of balance, the result is often weight gain, afternoon energy crashes, rising cholesterol, and early signs of insulin resistance. This is the same cluster of risk factors behind rising rates of type 2 diabetes, heart disease, and obesity across Asia.

The programme suits adults who want to address weight, blood sugar, or cholesterol concerns through sustainable lifestyle change rather than restrictive dieting. It is designed for people whose health markers are drifting in the wrong direction but who have struggled to correct them through willpower alone.

You may benefit from AMILI Optimise Plus if you:

1. Have borderline or elevated blood sugar, HbA1c, or fasting insulin readings
2. Carry excess weight or a high body fat percentage that has been difficult to shift
3. Are managing high cholesterol, particularly raised LDL or triglycerides
4. Experience persistent hunger, cravings, or energy crashes through the day
5. Have a family history of type 2 diabetes or cardiovascular disease
6. Want a data-led alternative to traditional calorie counting

The programme is not intended for people with active eating disorders, severe gastrointestinal disease, or those who are pregnant or breastfeeding. Your doctor will assess your suitability before starting the programme if you have any existing medical conditions.

Every participant receives five integrated components designed to work together over eight weeks. Each component feeds data into the next, so your plan keeps adapting as the programme unfolds.

1. Gut microbiome test – A stool-based gut microbiome test analyses your microbial diversity and identifies bacterial patterns linked to metabolic, digestive, and mental health.
2. Continuous glucose monitor (CGM) – A wearable sensor tracks your blood glucose in real time, revealing how specific meals and habits affect your readings.
3. Targeted probiotic supplement – A probiotic formulation selected based on the gaps and imbalances identified in your gut report.
4. Three video consultations with a certified coach – Structured sessions to review your data, set goals, and refine your plan.
5. Continuous chat support – Daily message-based coaching through the AMILI Optimise app for food logging, questions, and accountability.

The programme aims to produce measurable changes in weight, body composition, and metabolic markers while building habits you can carry forward. Because the plan is matched to your biology, participants tend to find it easier to sustain than restrictive diets.

Commonly reported outcomes may include:

• Sustainable weight change – Informed by your microbiome and glucose data rather than calorie restriction
• Appetite rebalancing – Gut-driven hormonal signals may rebalance and curb cravings
• Improved fat metabolism – A potential shift away from visceral fat storage
• Healthier cholesterol readings – Supported by changes in gut bacteria that support healthier cholesterol levels
• Steadier blood glucose – Fewer post-meal spikes and afternoon crashes

In AMILI's REMEDY study, all participants reported improved bowel form and regularity, and around 40 per cent experienced up to 3 kg of weight loss. Individual results vary based on starting point, adherence, and underlying health.

At ATA Medical, we are a pilot-phase clinic partner for AMILI Optimise Plus, offering pilot pricing for participants who join before the full Q3 2026 launch.

The metabolic health programme can also complement GLP-1 weight loss medications such as semaglutide and tirzepatide. A healthier gut microbiome may reduce common gastrointestinal effects of GLP-1 therapy, including nausea, bloating, and constipation, by supporting healthy digestion and gut lining function.

Microbiome-led nutrition may also help sustain the medication's benefits over time. Research suggests that a diverse gut microbiome may support the body's own GLP-1 production and promote more consistent weight management during and after treatment. This may make AMILI Optimise Plus a useful complement for patients already on GLP-1 therapy or planning to start.

Your doctor will assess your suitability before combining the programme with any GLP-1 medication.

"A programme built around your own microbiome and glucose data gives patients something generic diet advice cannot. By addressing metabolism at the biological level, the changes tend to last well beyond the eight weeks."
— Dr Leonard Leng

"A programme built around your own microbiome and glucose data gives patients something generic diet advice cannot. By addressing metabolism at the biological level, the changes tend to last well beyond the eight weeks."

— Dr Leonard Leng

• Tanjong Pagar Clinic
• Orchard Clinic
• Jurong Clinic
• Novena Clinic